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Metformin, commonly prescribed for diabetes, and proton pump inhibitors used for acid reflux can both reduce B12 absorption over time

Taniki N, Nakamoto N, Chu PS, Mikami Y, Amiya T, Teratani T, Suzuki T, Tsukimi T, Fukuda S, Yamaguchi A, Shiba S, Miyake R, Katayama T, Ebinuma H, Kanai T (2018) Intestinal barrier regulates immune responses in the liver via IL-10-producing macrophages

Dosage Range

It's attracted growing interest in research circles because of how directly it targets a specific enzymatic pathway - which makes it a useful tool for studying how NNMT activity influences downstream metabolic signalling at the cellular level

Ive been using for a few weeks and ordering another bottle soon

Fix: Commit to minimum 8 weeks, preferably 12 weeks