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The authors concluded "our data provide evidence that high dose intravenous vitamin C therapy has a positive effect on disease duration and reduction of viral antibody levels." (Mikirova 2014)

The overproduction of ROS in the mitochondria can damage cells and lead to various diseases and disorders

Paulis G

Among these, receptor-interacting protein kinase 1 (RIPK1) is the central mediator of signalling pathways that regulate cell survival and death [2]

Malateaspartate shuttle A biochemical system in which malate carries reducing equivalents generated in the cytoplasm in the form of NADH across the inner membrane of the mitochondrion which is impermeable to NADH for oxidative phosphorylation

Luo Y, Tian Y, Zhao C