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Beige adipocytes have some distinct thermogenic pathways, such as dissipation of the proton (H+) energy gradient through UCP1 in the mitochondria, futile calcium cycling through sarcoplasmic/endoplasmic reticulum Ca 2+ ATPase 2 b (SERCA2b) in the endoplasmic reticulum [2,3], and a futile creatine cycle through tissue-nonspecific alkaline phosphatase (TNAP) in the mitochondria [4-7]

J Cardiol 1991;21(2):493-504

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Third, older adults and individuals with cardiovascular concerns seeking carnitine for cardiac and vascular energy support the CarniPlex and PLCAR components address the cardiac and peripheral vascular dimensions of carnitine's benefits that are often more relevant than skeletal muscle fat metabolism for this population

doi: 10.1155/2014/474296 [DOI] [PMC free article] [PubMed] [Google Scholar] 110.Gross EC, Klement RJ, Schoenen J, DAgostino DP, Fischer D

Adjusted mean AC levels across the three groups were estimated from the mixed models, standardized differences between groups were reported using Cohens d tested in post-hoc pairwise comparisons