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Adv Enzyme Regul 2002;42:249-59

Tesomet is a fixed-dose combination of tesofensine with metoprolol (a beta-blocker), designed to attenuate the heart rate increase associated with tesofensine's noradrenergic effects

doi: 10.1016/j.ccell.2017.03.006 13 Sade-FeldmanMYizhakKBjorgaardSLRayJPde BoerCGJenkinsRWet al
& Stern, M

Taking a dose before bed can help "refill the tank," supporting the body as it clears out the oxidative byproducts of the day's activities

Liver models were treated by repeated daily dosing with vehicle control and TVX or LVX at 1 M, 10 M and 20 M
