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In these studies, high-dose niacin treatment restored NAD + levels and provided functional benefits in adult patients: remarkable decrease of liver fat, increase of mitochondrial respiration and biogenesis, muscle strength and exercise tolerance 15

doi: 10.1093/protein/6.1.109

& Ohta, S

This peptide can be fused to the N- or C-terminal of the target protein enabling the purification by a combination of several techniques including IMAC, IEX, aqueous two phase system (ATPS) and hydrophobic interaction chromatography (HIC)

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Contribution of mucosal maltase-glucoamylase activities to mouse small intestinal starch -glucogenesis