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Comparative efficacy of glucagon-like peptide 1 (GLP-1) receptor agonists, pioglitazone and vitamin E for liver histology among patients with nonalcoholic fatty liver disease: systematic review and pilot network meta-analysis of randomized controlled trials

The review addresses the potential for complementary supplements during GLP-1 therapy to support muscle health, nutrition, and overall wellness, including with ingredients such as multivitamins, protein supplements, creatine, HMB, antioxidants, fiber, and probiotics

But its important to know that this study was small and short-term

Both patterns can lead to successful long-term outcomes

Most side effects during the first week are mild to moderate in severity and do not require discontinuation of therapy

Mild fatigue during the first 6-8 weeks is common and usually reflects rapid metabolic shifts and reduced calorie intake