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doi:10.1186/1742-4690-5-27 Nolkemper S, Reichling J, Stintzing FC, Carle R, Schnitzler P

The efficacy of oral supplementation of vitamin B12 is limited by factors such as the absence of IF, gastric surgery, concomitant metformin, or antacid treatment

Yes, its an essential trace element

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It also provides additional benefit to neurons by providing some protection from inadequate oxygen and blood supplies, which may occur in the case of an injury