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Gastroenterology 154 , 14801493 (2018)

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HSP90 was rapidly induced by high temperature at 1 h (Figure 3A)
The pathological changes hidradenitis suppurativa causes seem to result from peripilar inflammation, leading to an accumulation of keratine and hair follicle obstruction, dilation and rupture

(2) Metals used in NPs may have poor biocompatibility, necessitating appropriate chemical modifications to enhance biocompatibility and reduce toxicity
