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In squamous cell carcinoma, CEBPB isoforms LAP/LIP drive proliferation by dysregulating cell cycle and differentiation pathways [147]
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Earlier experimental studies have shown that reactive oxygen species (ROS) and plasminogen activator inhibitor 1 (PAI-1) induced by initial insults penile tissues are remarkably increased in fibrotic plaques and then result in oxidative stress (Vernet et al., 2002
