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Following injury induction (a 0.8 centimeter osteoperiosteal defect was created in the middle of both radii), the experiments using bone marrow and the TRIS-BPC157 (6 rabbits per group) were carried out as follows: Saline (2 ml intramuscularly and 2 ml locally into each of the bone defects) treated injured animals were used as controls (group 1)

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Food & Drug Administration, 2023)

Bone turnover markers: In the simple weight loss group, OC decreased by 20% and CTX increased by 30%

In the sigmoidectomy group, 20 of 39 patients (51%) underwent primary anastomosis procedure and 19 (49%) underwent a Hartmanns procedure