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And CDCZA-treatment resulted in the highest cell inhibition rate, which was the synergy of Cu 2+ -mediated enhanced CDT and CDDP-mediated enhanced chemotherapy

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FSP1-mediated defense mechanism Originally identified as apoptosis-inducing factor (AIF) mitochondria-associated 2 due to its resemblance to AIF, FSP1 has since been characterized through detailed studies as playing a crucial role in preventing ferroptosis rather than facilitating apoptosis (24,152)