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FPN is widely expressed in intestinal epithelial cells, hepatocytes, splenic macrophages, and the placental barrier (Rishi and Subramaniam, 2021)

Autism Res 2:98108 Guo T, Chen H, Liu B, Ji W, Yang C (2012) Methylenetetrahydrofolate reductase polymorphisms C677T and risk of autism in the Chinese Han population

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In addition, oxidative stress results in alterations in the local immune response, increasing the risk of infections and exacerbations, which, in turn, may accelerate lung function decline

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doi: 10.1093/oxfordjournals.molbev.a026159 128 HoltenE
