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100( 3): S440

Jul/Aug 2019;27(4):202-207

[Infantile encephalopathy associated with the MELAS A3243G mutation

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doi: 10.1186/s40168-021-01046-5 47 ChynowethJHoskingJJefferyAPinkneyJ

Notably, TMAO also amplifies ERS markers such as heat shock protein 60 and glucose regulated protein 78kD in macrophages, correlating with elevated toll-like receptor 4 expression and proinflammatory cytokine production (e.g., TNF-, IL-6) (88, 89)