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Based on the relationship between lipid peroxidation and cell death, molecules that increase production of peroxides to trigger cell death might be important for removing tumor, and molecules that prevent or eliminate peroxides might be important for defending inflammatory diseases

Many molecular pathways that promote the development of NAFLD, such as early IR, gut microbiota and metabolites, are involved in hepatocyte lipotoxic stress and injury, and further contribute to hepatocyte senescence and death, stellate cell activation and fibrosis (Wang et al., 2023)

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2 Structure and activation of CPKs CPKs are pivotal signaling molecules in plants, first cloned and characterized in soybean in 1987 ( Arabidopsis , maize, Saccharina japonica , and rice, respectively ( 2+ sensing and signal transduction within a single polypeptide ( 2+ signaling networks across plant species, particularly in relation to immune adaptation and stress tolerance ( CPKs are composed of a single polypeptide chain organized into four domains: the variable N-terminal domain (VNTD), the Ser/Thr kinase domain (catalytic domain), the autoinhibitory junction domain, and the C-terminal calmodulin-like regulatory domain (CaMLD) ( Figure 1A )

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The authors emphasise the need for education, improved access to comprehensive information, and support from the healthcare team for patients diagnosed with type 1 diabetes in the context of low-carbohydrate diets [186]