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[DOI] [PubMed] [Google Scholar] 55.Boutaud O, Roberts LJ., 2nd Mechanism-based therapeutic approaches to rhabdomyolysis-induced renal failure

As a System X c inhibitor, Sorafenib is the only anticancer drug that causes ferroptosis in patients with HCC (Louandre et al., 2013)

Marengo et al

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This sequential/parallel action provides rationale for combination use in research settings

The small thiol present in highest concentration in the cytoplasm is glutathione (GSH), a tripeptide glycine-cysteine-glutamic acid (Figure 2): the SH group of its cysteine is extremely sensitive to oxidation, mainly by peroxides