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Description
See here: Vitamin B12 and Child Development While adults can tolerate an insufficient supply of B12 for quite some time without developing severe symptoms, this is not the case when it comes to children due to their lack of B12 stores in the body

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This pattern reflects the underlying biology rather than treatment failure

Proteases can be tagged with biotin, GST tag or even His tags to facilitate their removal.

J Biol Chem 284:436445
