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CHIMERA model has also been more recently applied to gyrencephalic ferrets, also reporting axonal injury based on enhanced APP signal, and neurofilament M (RMO) levels, as well as increase in tau phosphorylation AT180 at the base of the sulci by using a higher intensity impact, in turn offering a possible CTE animal simulation (Krieg et al., 2023)

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However, through the process of fragmentation, a smaller derivative called Ac-SDKP is formed

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It is important to note that these dosage suggestions are not based on scientifically validated evidence and should be considered speculative

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Sometimes, you might need them weekly

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