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Sun et al., 2018

To limit free metal concentrations, the synthesis of specific chelators and subsequent sequestration of metal complexes are of major importance

By comparing the differentially expressed proteins (DEPs) of the two groups at 1, 3, and 7 days post - treatment, it was revealed that DP consistently and significantly downregulated the expression of the Interleukin6 (IL-6) and the cytokine-Induced neutrophil chemoattractant3 (CINC-3), while significantly upregulating the expression of the neurotrophic factor ciliary neurotrophic factor (CNTF)