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J Appl Bacteriol R18 Dolan SK, Wijaya A, Geddis SM, Spring DR, Silva-Rocha R, Welch M (2018) Loving the poison: the methylcitrate cycle and bacterial pathogenesis

Molecular size, enzymatic degradation, saliva, short contact time, and the mucosal barrier can all limit uptake

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The disease can actually go into complete remission for some people
