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However, where mutant enzyme expression occurs, the most prevalent syndromes include hemolytic anemia, either with or without hepatosplenomegaly

Minerva Gastroenterol Dietol
Journal of the American Chemical Society, 103 (21), 6472-6477

doi: 10.1016/s1382-6689(01)00081-3

To summarize, we found that AST can ameliorate DED by reinforcing the SLC7A11/GPX4 pathway, which mainly affects oxidative stress, autophagy, and ferroptosis processes

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