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Primary rat astrocytes were incubated with a range of MOIs (multiplicity of infection) to estimate the viral load necessary for ~10% of astrocytes to express Cx43-TID
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In addition, the use of transcriptomic and genomic approaches in patients with well-characterized DILI has provided important insights into the involvement of the host immune response in the pathogenesis of hepatotoxicity associated with the administration of flucloxacillin, lumiracoxib or ximelagatran
