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To experimentally modulate arginase activity, specific inhibitors have been developed: N-hydroxy-L-arginine (NOHA) or N-hydroxy-nor-l-arginine (nor-NOHA), and boronic acid derivatives, such as 2(S)-amino-6-boronohexanoic acid (ABH), and S-(2-boronoethyl)-l-cysteine (BEC) s[229]

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High remission rate, short remission duration in patients with refractory anemia with excess blasts (RAEB) in transformation (RAEB-t) given acute myelogenous leukemia (AML)-type chemotherapy in combination with granulocyte-CSF (G-CSF)

M., Zatarain, J

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