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Both omega-3 and omega-6 PUFAs play significant roles in cardiovascular, inflammatory, metabolic, neurological, and psychiatric health (14, 49, 50)

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Current drugs in development target mitochondrial metabolism, including NAD+/NADH ratio, calcium influx, and fatty acid oxidation

[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S