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Intervertebral Disc Composition The IVD is comprised of three substructures: the nucleus pulposus (NP), annulus fibrosus (AF), and two endplates of hyaline cartilage on the superior and inferior sides of the disc referred to as the cartilaginous endplates (CEP) (Figure 1A)

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Development of a novel in vivo corneal fibrosis model in the dog