glutathione reductase disulfide bridge Dual pathways for bond reduction in the cytoplasm of E. coli What is the mechanism of

is supported by an NHMRC Investigator Grant (GNT2009843)

doi:10.1016/j.ctim.2018.09.015

Human and environmental impacts of nanoparticles: a scoping review of the current literature

K., Kim S., Kwon D., Koh J., Kim Y

GPx-1 is the cytosolic isoform that is expressed in most tissues, although there are other isoforms with tissue-specific distribution.5 There are numerous studies on the role of oxidative stress and antioxidant defenses in the thyroid gland, adipocytes, and orbital muscle cells,6 plasma, erythrocytes,5,7,8 or urine9 of patients with Graves disease, but the expression of antioxidant enzymes or the redox status in PBMC has not been evaluated

Lysosomal instability and release of lysosomal content into the cytosol have been proposed as a mechanism by which lysosomes can contribute to APAP-induced hepatotoxicity