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Iodine has also been shown to interact with amyloid fibrils, amyloid polymorphs and form complex with mature insulin amyloid fibrils (Hiramatsu et al., 2020

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When deficiency is suspected based on clinical features (fatigue, paraesthesia, cognitive changes) or risk factors (vegan diet, gastric surgery, certain medications), serum B12 measurement guides appropriate intervention
Lancet 389 , 23282337 (2017)

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