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These include: Oral Supplements : Pernicious anemia can be treated with over-the-counter B12 supplements, which work best for those with slight to moderate deficiency

Serotonin is not the primary driver of anhedonia that is largely dopamine but it plays a supporting role in emotional baseline and reward sensitivity

The severity of the vitamin B12 deficiency Presence of underlying health conditions Patients response to initial treatment Age and weight considerations Healthcare providers can adjust the vitamin B12 injection dosage based on these factors

For some patients, a wellness plan includes routine vitamin injections, IV infusions, or peptide therapy

10.1111/hex.13152

This study answered that question with a clear yes and mapped the specific biological pathways involved