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The antioxidant activity of GSH intermediated via thiol (-SH) of its cysteine residue upon its interaction with ROS or electrophiles and the GSH oxidized to GSSG (oxidized Glutathione), the GSSG will reduce to GSH by Glutathione reductase (GR), the activity of GR is therefore very important to keep the antioxidant power of mammalian cells, while GSH/GSSG ratio is an indicator for redox balance in the cell

The first is as a co-factor or sulfur source for the production of compounds such as camalexin and glucosinolates

[DOI] [PMC free article] [PubMed] [Google Scholar] 111.van Bloemendaal L, Veltman DJ, ten Kulve JS, et al

Calcium oxalate crystals are recognized by macrophages as foreign particles, triggering the proinflammatory state and macrophage response.[ref][ref] A 2021 study looked at the inflammatory response to dietary oxalates

Biometals 21, 367372

Hamdi, H