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[DOI] [PubMed] [Google Scholar] 213.Rung J.P., Carlsson A., Rydn Markinhuhta K., Carlsson M.L

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It can be caused by vitamin B deficiency

Over time, this may lead to dull-looking skin, uneven tone, and dark spots

On top of this, glutathione production drops significantly as we age, leading to an inevitable imbalance of too much toxic stress and inflammation and not enough antioxidants to counter it

If none of those apply and you eat a varied diet that includes animal products, your B12 status is less likely to be a concern during treatment