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Collectively, these data suggest that the induction of ceramide biosynthetic enzymes triggers SKN-1 activation in response to germ cell absence

Transport of lipids from golgi to plasma membrane is defective in tangier Disease patients and Abc1-deficient mice

Trends Genet 19:269277 Hinderer C, Katz N, Buza EL et al (2018) Severe toxicity in nonhuman primates and piglets following high-dose intravenous administration of an AAV vector expressing human SMN

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