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Mashaghi A, Marmalidou A, Tehrani M, Grace PM, Pothoulakis C, Dana R (2016) Neuropeptide substance P and the immune response

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For example, an exercise intervention may reduce pain, but the RCT cannot isolate whether the mechanism was increased strength, flexibility, neuromodulation, or expectancy effects

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Key Takeaway: Both salts deliver the same therapeutic agent, but their pharmacokinetic profiles differ potassium for speed, sodium for sustained control