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To date, established treatments are only symptomatic in nature, trying to counterbalance the neurotransmitter disturbance of the disease

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[Abstract]2024 Dec 31:111368

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On the one hand, this NADPH production is important for maintaining the redox balance in the cells by producing antioxidants that protect immune cells from ROS

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145 When ECs maintain robust circadian BMAL1 expression, SMAD3 phosphorylation and downstream TGF-/SMAD3 signaling components display synchronized circadian oscillations, thereby preserving rhythmic bone metabolism

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