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De Marchi F, et al
Plays a role in the metabolism of fatty acids as part of an active lifestyle
They discovered that the protein kinase R-like endoplasmic reticulum kinase signaling was demanded for cardiac valve formation via CPT2-dependent FAO and EndoMT
TML is then hydroxylated by 6-N-trimethyllysine dioxygenase (TMLD), which is located in the mitochondrial matrix, to form 3-hydroxy-6-N-trimethyllysine (HTML)
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