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Toscano, F

In addition, pharmacogenomics studies could be useful in the identification of mutations in genes influencing antitumor drug metabolism, and this could also be an important source of data for optimal dosing of these drugs in patients [101]

A Preliminary Report

Serrano added that older populations were also at higher risk, as cases of B12 deficiency increase with age

Onstad MA, Schmandt RE, Lu KH (2016) Addressing the role of obesity in endometrial cancer risk, prevention, and treatment

These tests may require specialist laboratory referral Holotranscobalamin (active B12) where available, may be used as a second-line test when standard B12 results are borderline Intrinsic factor antibodies to identify pernicious anaemia, the most common cause in the UK Parietal cell antibodies may be useful if intrinsic factor antibodies are negative but pernicious anaemia is still suspected Thyroid function and folate levels to exclude other causes of similar symptoms According to current UK guidance, patients presenting with neurological symptoms suggestive of B12 deficiency should not have treatment delayed whilst awaiting test results
