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In fact, studies show that B12 deficiency is one of the leading nutrient deficiencies in the world, and is also a major health concern in many parts of the world, including the US, Mexico, Central and South America

Because cobalamin in normally absorbed from food through the gastrointestinal tract, chronic diseases that adversely affect the ability of the intestines to absorb nutrients (inflammatory bowel disease is an excellent example) can lead to cobalamin deficiency

Fungal Genet Biol

Shiitake Mushroom (Lentinula edodes) Contains moderate levels of EGT while also promoting immune and cardiovascular health

Cell 144 , 439452 (2011)

Its hallmark pathological features including cartilage degradation, subchondral bone sclerosis, osteophyte formation and synovial inflammation, are fueled by a complex interplay of inflammatory cascades, oxidative stress, and mechanical stress imbalance (57)