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Reduction in membrane surface by means of exocytosis during maturation of reticulocytes enables the cells to reduce or completely eliminate a number of receptors and ion transporters which play an active role in differentiation of erythroid precursor cells and are no longer required by mature RBC

Gao L, Li Z, Chang S, Wang J (2014)

in particular, they employed a Tetrahedral framework nucleic acid-VitB12 complex (TVC), which was aimed at overcoming possible limitations due to the bloodbrain barrier and TC availability, obtaining good results on disease symptoms [137]

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doi: 10.3390/ijms24097991 53 FornaroM.CaiazzaC.BilleciM.BerkM.MarxW.Balanza-MartinezV.et al

There is also evidence that enzymes regulating GSH, GTX, serve protective roles against platelet hyperactivity and thrombosis