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Clusters Bu, HG, and DP were divided by specified markers: CD34, Krt5, Ccnd1, Lhx2, Enpp2, and Wif1 (Fig

The grade of re-pigmentation improved overall at each follow-up visit (Table 2)

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These changes included mucosal erosion, ulcerative lesions, deformation and distortion of colonic recesses, extensive infiltration of inflammatory cells (primarily lymphocytes and neutrophils) in the mucosa and submucosa, and depletion of goblet cells

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One milliliter of sample was withdrawn at each time point (0.5, 1, 2, 4, 8, 12, 24, 36, and 48 h) from the Franz cell receptor chamber and refilled with an equal quantity of fresh PBS (pH 7.4)