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( B ) Ppargc1a mRNA levels in AC16 cells treated with 50 M rosiglitazone (PPAR agonist), 50 M WY-14643 (PPAR agonist), a combination of rosiglitazone and WY-14643, or a combination of rosiglitazone, WY-14643, and 10 M MK886 (PPAR antagonist) ( B

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Patient selection depends on individual goals and medical history