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[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Mourkioti F, et al

Glutathione and the -glutamyl cycle The synthesis, transport and catabolism of GSH occur in a series of enzymatic steps and transports of membrane that are collectively called -glutamyl cycle (Figure 5) (1, 74, 75)

[136] Patients with hepatic impairment may require modified dosing regimens due to ondansetrons extensive hepatic metabolism

For instance, intragastric administration of EGCG for 60 days prevented cognitive deterioration in senescence-accelerated mice and decreased the accumulation of -amyloid, which plays a fundamental role in Alzheimers disease [235]

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Simultaneously, drug binding activates NOX3, which is highly expressed in cochlear tissue, thereby generating superoxide anions (Schacht et al., 2012