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Well, let's get back to that study we mentioned at the beginning of this post

High-throughput capability As GPCRs are an integral part of many cell signaling pathways, they are a major target for drug discovery and screening

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GO molecular function analysis of downregulated genes in JHU083-treated TAMs Notably, by evaluating the GO pathway analysis for biological processes, we found that lysosome- and Toll-like receptor (TLR) signalingrelated genes were significantly upregulated with drug treatment between TAMs isolated from tumors of JHU083-treated and untreated mice (Table 2)

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