glutathione reductase gout - an overview Targeting uric acid: a promising

Kinetic studies indicated that the inhibition was not competitive with the substrate

Chen, B.H., et al

Gomez DR, Cox JD, Roth JA, Allen PK, Wei X, Mehran RJ, Kim JY, Swisher SG, Rice DC , Komaki R

Sleep Med 8 , 613622, (2007)

In the DCA plot, the x-axis represents the risk threshold and the y-axis represents the net benefit, with higher curves indicating greater clinical decision-making value at the corresponding risk thresholds

In this study, the modeled AtPCS1 structure revealed a pocket in proximity to the first substrate-binding site, consisting of three loops containing several conserved amino acids, including Arg152, Lys185, and Tyr55