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Gamma () -Glutamyl Cyclo Transferases (GGCTs) catalyse the breakdown of GSH in Cys-Gly and 5-oxoproline (5-OP) under environmental stress conditions

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Intriguingly, specific AFG3L2 missense variants clustering in the ATPase domain are linked to DOA, while variants in other protein regions cause spinocerebellar ataxia type 28, demonstrating a striking domain-specific disease association [168]

Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury