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It includes bioflavonoids from rose hips, quercetin, and hesperidin for additional antioxidant-like support

The actions of hCG are exerted by binding of the hormone to the LHCGR in the luteal cells of the ovary

doi: 10.3168/jds.2008-1901

However, in the SW620/Ad300 (P-gp-overexpressing) and S1-M1-80 (ABCG2-overexpressing) colon cancer xenograft models, the combination of regorafenib and paclitaxel or the combination of regorafenib and topotecan resulted in a synergistic antitumor effect which demonstrated that regorafenib overcame the resistance of paclitaxel to P-gp-overexpressing SW620/Ad300 tumors and the resistance of topotecan to ABCG2-overexpressing S1-M1-80 tumors in mice (Wang et al., 2017b

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