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Pharmacokinetics and Receptor Affinity A defining characteristic of this specific research peptide in a laboratory setting is its highly optimized pharmacokinetic profile

[PubMed: 19477698] (Analysis of 20 cases of suspected kava hepatotoxicity reported to German regulatory agency, using RUCAM to assess causality, found low level of evidence largely because of lack of information on clinical course [dechallenge] and exclusion of other causes, and use of other potentially hepatotoxic medications)

Causes include granulomatous, postpartum, and silent thyroiditis

Despite a promising in vitro antitumor activity, the development of this therapy faced off serious side effects, limiting its potential development as anticancer therapy

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