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Side effects are rare but may include mild irritation at the injection site or dizziness

-Lapachone (ARQ761 in clinical form) undergoes a futile NQO1-mediated redox cycle, where the drug forms an unstable hydroquinone that spontaneously regenerates to the parent compound in a two-step oxygenation process [44,80]

10.1016/j.psychres.2020.113471 3

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4 The anti-inflammatory properties of VIP have been demonstrated in animal models of several immune disorders such as septic shock, 5 multiple sclerosis, 6 rheumatoid arthritis (RA), 7,8 and CD