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elegans ), to inhibit the build-up of PI(4,5)P 2 on endosomes

Notably, 27-HC-resistant cancer cells acquire ferroptosis resistance, leading to increased tumorigenicity and more metastatic properties, although how these lipids specifically inhibit ferroptosis is unclear 129

Two scientists at the University of Arizona, dermatologist Mac Hadley and chemist Victor Hruby , were working on a problem that sounded simple: skin cancer