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147 In a randomized controlled trial in 156 subjects with a history of a single DVT episode, 150 mg pycnogenol was as effective as compression stockings at reducing edema after one year, but was associated with better compliance due to the discomfort of compression stockings

Symptoms may include fatigue, weakness, memory problems, difficulty concentrating, mood changes, numbness or tingling in the hands and feet, and difficulty maintaining balance

doi:10.1093/jn/133.11.3972S

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