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Their effects on CVDs are strain-specific and depend on the dose, duration, and specific population studied (144, 145)

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[DOI] [PubMed] [Google Scholar] 38.Glatz JF, Bonen A, Ouwens DM, Luiken JJ

Through the inhibition of ACC and the activation of MCD, MAPK diminishes malonyl-CoA levels, leading to a reduction in fatty acid synthesis and an increase in fatty acid catabolism ( Nuclear factor erythroid 2-related factor 2 (Nrf2) is a critical transcription factor in cellular antioxidant responses (Sul and Ra, 2021)

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