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The C1 metabolism modeling, for example, predicted the temporal behavior of formaldehyde, formate, sarcosine, glutathione, as well as many other key biomolecules involved in C1 metabolism, which may be hard to measure experimentally [8]

Specifically, it was originally believed that glycosylases were the only DNA-binding enzymes that utilise FeS clusters [2, 13]

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However, several limitations should be acknowledged

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High intraocular pressure is the main prognostic factor in glaucoma, even a slight reduction in eyeballs tension results in significant improvement in the disease course