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In addition, it has been debated whether erythrocyte membrane injury could promote the thrombotic complications frequently observed in COVID-19 patients [342], and that reduced deformability of erythrocytes may contribute to inflammation and hypoxia in COVID-19 patients [343]

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Moreover, since this function was inherited from engulfed prokaryotes which became mitochondria, the melatonin synthesizing capacity was presumably retained in these organelles to the present day

Two previous randomized, controlled trials have reported increased antioxidant capacity and decreased DNA fragmentation in the sperm of males experiencing infertility who were supplemented with omega-3 fatty acids